Cliff and Otis, two friends in the film "Best Friends Cliff and Otis" plan to get rich quickly by stealing from drug dealers. However, they decide not to follow their original plan and instead spend the night partying. This leads the audience to see that the "bad guys" are not as bad as they initially thought. The film is a typical dramedy filled with Germans, Jesus, banjos, bongos, beers, and bongs.