Simon (Brett Goldstein) and Laura (Imogen Poots) are best friends who embark on a journey together, taking a test that guarantees to match them with their soulmate. As Laura's new man comes into her life, Simon begins to understand just how much he cares for her, even if he isn't ready to admit it yet.
Despite their differences, Simon and Laura must navigate the path destiny has laid out for them, before it all becomes too much and their love spills over into their complicated lives. All of You utilizes an innovative structure that presents a brief glimpse into the main characters' lives before whisking us into the future, repeating this cycle to offer snapshots of a love that lasts a lifetime.